Dose are individualized depending on the patient condition. Please consult your doctor or pharmacist for the suggestion of treatment for your hypertension. Once you started your hypertension medication, take the medication regularly and accordingly.
Generally, it is advisable to be taken with meals to reduce stomach discomfort. Otherwise, refer product insert for specific instruction:
|With or without food|
Mechanism Of Action
Centrally acting sympatholytics block sympathetic activity by binding to and activating alpha2 (?2)-adrenoceptors. This reduces sympathetic outflow to the heart thereby decreasing cardiac output by decreasing heart rate and contractility. Reduced sympathetic output to the vasculature decreases sympathetic vascular tone, which causes vasodilation and reduced systemic vascular resistance, which decreases arterial pressure.
This class of antihypertensive is commonly use for the management of hypertension in pregnancy.
Side effects for each drugs are individualized. Most common side effects for the drug is listed below:
|Generic Name||Possible common side effects include|
|Methyldopa||Sedation, headache, weakness, dizziness, orthostatic hypotension, gastrointestinal discomfort, impotence|
Consult your doctors or pharmacists if you are facing any side effects from the antihypertensive drugs that you are taking.
Advisable to be keep in the original envelopes with instructions on how to take clearly stated on labels. Keep at room temperature otherwise, refer product insert for specific temperature storage.
For further information, refer MyHealth web site ‘Cara Penyimpanan Ubat Yang Betul’.
- Mechanism of Action of Angiotensin Converting Enzyme http://www.cvpharmacology.com/Acilliary/search
- British National Formulary (BNF) 61 March 2011
- MIMS 128th Edition 2012
- Mechanism of Action of Centrally Acting Symphatolytics http://www.cvpharmacology.com/Acilliary/search
- ‘Cara Penyimpanan Ubat Yang Betul’ (http://www.myhealth.gov.my/v2/index.php/my/ubat-a-anda/umum/cara penyimpanan-ubat-yang-betul)
|Last Reviewed||:||2 March 2016|
|Writer||:||Pn. Azura Binti Musa|
|Translator||:||Pn. Azura Binti Musa|
|Accreditor||:||Dr. Siti Norlina Binti Md. Said|