Wednesday , September 23 2020
msen
Utama > Hypertension > Beta Blocker

Beta Blocker

Indication

Antihypertensive

Dose

Doses are individualized depending on patient’s condition. Please consult your doctor or pharmacist for suggestion of treatment for your hypertension. Once you have started with your medications for hypertension, take the medications regularly and according to the instructions.

Administration

Generic Name Administration

Atenolol

atenolol

With or without food.

Metoprolol

metoprolol

With or without food.
Labetalol With food, preferably take after meals

Carvedilol

carvedilol

With food.
Bisoprolol With or without food.

Mechanism Of Action

Beta blockers block the beta-adrenergic receptors that produce epinephrine, also known as adrenaline, (a hormone or neurotransmitter that constricts the blood vessels). Beta blockers also reducing blood pressure help the heart to beat slower with less force.

Side Effects

Side effects for each drugs are individualized. Most common side effects for each drugs are listed below:

Generic Name Possible common side effects include
Atenolol Dizziness, vertigo, nausea, fatigue
Metoprolol Fatigue, headache, dizziness, peripheral coldness extremities, insomnia, gastrointestinal disturbance, impotence
Labetalol Postural hypotension (a drop in blood pressure due to a change in body position /posture), tingling (decreased or abnormal sensations caused by altered sensory nerve function), gastrointestinal disturbance, headache, tiredness, impotence, insomnia
Carvedilol Dizziness, headache, fatigue, sleep disturbance, sleep disturbance, impotence
Bisoprolol Bradycardia (slower the heart rate / resting heart rate of under 60 beats per minute), fatigue, dizziness, headache, gastrointestinal discomfort, hypotension

Consult your doctor or pharmacist if you are facing any side effects from the antihypertensive drugs that you are taking.

Storage

Advisable to keep in the original envelope with instruction on how to take clearly stated on labels. Keep at room temperature otherwise, refer product insert for specific temperature storage.

References

  1. Cardiovascular Pharmacology Concepts
  2. http://www.cvpharmacology.com/cardioinhibitory/beta-blockers
  3. http://pharmacologycorner.com/mechanism-of-action-video
  4. British National Formulary (BNF) 61 March 2011
  5. MIMS 128th Edition 2012
  6. Mechanism of Action of Beta Blockers | eHow.com http://www.ehow.com/facts_6979507_mechanism-action-beta-blockers
Last Reviewed : 2 March 2016
Writer : Azura Binti Musa
Translator : Azura Binti Musa
Accreditor : Dr. Siti Norlina Binti Md. Said

Baca Juga

Pulmonary Arterial Hypertension And Congenital Heart Disease

Pulmonary Arterial Hypertension (PAH) is high blood pressure in the vessels that carry blood from the heart to the lungs (the pulmonary artery and its